Advanced Genetic Testing in Madurai & Tamil Nadu
NABL Accredited • ICMR Approved • State-of-the-Art Molecular Genetics Laboratory
Precision Medical Genomics & Diagnostics
Empowering Clinical Decisions with Advanced DNA Sequencing in Madurai
At Advanced Diagnostics Lab, we bring state-of-the-art molecular biology directly to patient care. Our NABL-accredited facility utilizes high-throughput Next-Generation Sequencing (NGS) to provide critical diagnostic clarity. From resolving rare undiagnosed conditions with Whole Exome Sequencing to guiding targeted therapies through precise Oncology and Pharmacogenomics panels, we are committed to the future of personalized medicine.
Core Clinical Diagnostics & Oncology
Human Whole Genome Sequencing (WGS)
Clinical Utility: The most comprehensive genetic test available. Sequences 100% of the DNA (both coding and non-coding regions) to identify rare genetic disorders, complex polygenic health risks, and structural variants. The gold standard for difficult-to-diagnose cases.
Methodology NGS (30x Depth)
Sample Type Blood (EDTA)
Turnaround Time 6 – 8 Weeks
Fasting Req. No
₹75,000
Book NowClinical Whole Exome Sequencing (WES)
Clinical Utility: Targets the ~1-2% protein-coding regions (exons) of the genome where up to 85% of disease-causing mutations occur. Highly cost-effective for diagnosing rare pediatric, neurological, and hereditary genetic conditions.
Methodology Targeted NGS (100x Depth)
Sample Type Blood / Buccal Swab
Turnaround Time 4 Weeks
Fasting Req. No
₹18,000
Book NowComprehensive Hereditary Cancer Panel
Clinical Utility: Evaluates germline mutations across 100+ genes (including BRCA1, BRCA2, PALB2, MLH1) to assess the inherited risk of breast, ovarian, colorectal, and prostate cancers. Vital for proactive surveillance and family planning.
Methodology NGS Panel + MLPA
Sample Type Blood / Saliva
Turnaround Time 3 Weeks
Fasting Req. No
₹18,000
Book NowOncology Liquid Biopsy (Targeted Panel)
Clinical Utility: Non-invasive analysis of circulating tumor DNA (ctDNA) to detect somatic mutations (e.g., EGFR, KRAS, ALK). Enables oncologists to match patients with precise targeted therapies and monitor Minimal Residual Disease (MRD) over time.
Methodology Ultra-Deep NGS
Sample Type Blood (Plasma)
Turnaround Time 10 – 14 Days
Fasting Req. No
₹40,000
Book NowAdvanced Cardiogenomics Risk Panel
Clinical Utility: Assesses genetic risks for inherited cardiovascular conditions, including Familial Hypercholesterolemia, Hypertrophic Cardiomyopathy (HCM), and Long QT syndrome. Crucial for families with a history of sudden cardiac arrest.
Methodology Targeted NGS Panel
Sample Type Blood (EDTA)
Turnaround Time 3 – 4 Weeks
Fasting Req. No
₹19,000
Book NowComprehensive Pharmacogenomics (PGx)
Clinical Utility: Analyzes how genetic variations in enzymes (like CYP450) affect your body’s ability to metabolize specific drugs. Replaces “trial and error” prescribing for psychiatry, cardiology, and oncology, preventing severe adverse drug reactions.
Methodology Microarray / PCR
Sample Type Buccal Swab / Blood
Turnaround Time 2 – 3 Weeks
Fasting Req. No
₹15,000
Book NowPreventative Health & Lifestyle Genomics
Reproductive & Carrier Screening
Clinical Utility: Identifies if prospective parents carry mutations for severe autosomal recessive conditions (e.g., Cystic Fibrosis, Thalassemia, SMA). Also investigates genetic causes of recurrent pregnancy loss and infertility.
Methodology NGS + Karyotyping
Sample Type Blood (Both Partners)
Turnaround Time 3 Weeks
₹28,000 (Couple)
Book NowAdvanced Gut Microbiome Mapping
Clinical Utility: Maps the DNA of trillions of bacteria in your digestive tract to identify dysbiosis linked to IBS, inflammation, and metabolic issues. Provides personalized dietary interventions for holistic health.
Methodology 16S rRNA Sequencing
Sample Type Stool Sample
Turnaround Time 4 Weeks
₹9,500
Book NowNutrigenomics & Diet DNA Profile
Clinical Utility: Understand your body’s genetic response to macronutrients and vitamins. Reveals predispositions to lactose/gluten sensitivities and helps craft the ultimate personalized nutrition plan for weight management.
Methodology Targeted SNP Array
Sample Type Saliva Swab
Turnaround Time 3 Weeks
₹12,500
Book NowClinical Genomics FAQ & Knowledge Base
What is the difference between Whole Exome (WES) and Whole Genome Sequencing (WGS)?
Whole Exome Sequencing (WES) focuses strictly on the protein-coding regions of your genes (about 1-2% of your DNA), where the vast majority of known disease-causing mutations reside. Whole Genome Sequencing (WGS) maps 100% of your DNA, including the non-coding regions, offering a broader view but often generating complex data that requires extensive interpretation.
Why is Pharmacogenomics (PGx) testing recommended?
Because human genetics vary, a drug that works perfectly for one patient might cause severe side effects in another. PGx testing analyzes your metabolic enzymes. If you are a “poor metabolizer” of a specific drug, it may build up to toxic levels; if you are an “ultra-rapid metabolizer,” the drug may clear your system before it can be effective. PGx guides doctors to the right drug and the right dose from day one.
How does an Oncology Liquid Biopsy assist in cancer treatment?
Traditional tissue biopsies require surgical procedures. A Liquid Biopsy is a simple blood test that isolates circulating tumor DNA (ctDNA) shed by tumors. This allows oncologists to rapidly identify actionable mutations (like EGFR or ALK), select targeted therapies, and monitor if the tumor is developing resistance to treatment over time.
Who should consider the Hereditary Cancer or Cardiogenomics Panels?
These panels are highly recommended for individuals who have a strong family history of early-onset cancers (e.g., breast cancer before age 50) or sudden, unexplained cardiac events in close relatives. Identifying a pathogenic mutation allows for early screening, prophylactic measures, and preventative care for the entire family.
Exome Sequencing
A comprehensive genetic test that analyzes all protein-coding regions of your DNA to identify mutations linked to inherited diseases and complex health conditions.
- Detects rare genetic disorders
- Provides detailed DNA analysis
- Supports accurate diagnosis of unexplained conditions
- Helps guide personalized treatment plans
Cancer Panels
Targeted genetic testing to identify mutations associated with various cancers, helping assess risk, support early detection, and guide treatment strategies.
- Identifies inherited cancer risks
- Supports early detection and prevention
- Helps in targeted therapy decisions
- Monitors genetic changes linked to cancer
Gut Microbiome
Analyzes the genetic makeup of gut bacteria to provide insights into digestion, immunity, metabolism, and overall gut health.
- Evaluates gut bacterial balance
- Supports digestive health improvement
- Provides personalized diet insights
- Helps boost immunity and metabolism
Personalized Genomics
A tailored genetic analysis that offers insights into how your body responds to diet, lifestyle, medications, and fitness for optimized health outcomes.
- Personalized health and nutrition guidance
- Insights into fitness and lifestyle optimization
- Helps understand drug response (pharmacogenomics)
- Supports preventive and precision medicine